Module 3

Conversion Chemistry

The Complete Cannabinoid Conversion Directory

WKU's flagship advanced module. 13 units, 50+ lessons covering every viable cannabinoid conversion pathway: D9, D8, D10, CBN, HHC, THCP, THCV, THCA flower, piatella, plus complete catalyst comparison, byproduct troubleshooting, and regulatory positioning.

3 units13 lessons60-80 hours estimated

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Unit 1

Structural Fundamentals

The cannabinoid skeleton, numbering systems, ring closure chemistry, and the catalyst and solvent principles that govern every conversion reaction.

3.1.1The Cannabinoid Skeleton: Structure, Numbering, and the Double Bond That Changes Everything🔒

3.1.2Ionic Reactions: Acids, Carbocations, Cyclization, and Regiochemistry🔒

3.1.3Radical Reactions: Free Radicals, Chain Mechanisms, and Allylic Selectivity🔒

Unit 2

Beginner Conversions

Beginner friendly methods to convert or create psychoactive cannabinoids from CBD.

3.2.1Zeolite Clinoptilolite Conversion — CBD to THC🔒

3.2.2pTSA/Heptane Δ8-THC Conversion🔒

3.2.3Amberlyst 15 Melt Conversion: CBD to Δ8-THC🔒

3.2.4CBD-Derived Piatella: Distillate and Kief Matrix Formation🔒

3.2.5Small-Scale Maltodextrin Formulation: Cannabinoid-Infused Powder🔒

Unit 3

Intermediate Conversions

Production-scale conversions requiring reactor equipment, atmosphere control, analytically-driven endpoints, and active quench protocols.

3.3.1HCl/Ethanol Conversion: CBD Isolate to Δ9-THC🔒

3.3.2AlCl3/DCM Conversion: CBD Isolate to Δ9-THC🔒

3.3.3SeO2 Allylic Oxidation: Δ8-THC to 11-Hydroxy-THC🔒

3.3.4TfOH/DCM Total Synthesis of THCB (Δ9-Tetrahydrocannabutol)🔒

3.3.5pTSA/Heptane Total Synthesis of THCP (Δ8-Tetrahydrocannabiphorol)🔒